HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Quinuclidine, 3-amino-, dihydrochloride → N-(1-Azabicyclo[2.2.2]oct-3-yl)-7-quinolinecarboxamide hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Quinuclidine, 3-amino-, dihydrochloride | HCID 197853 | — |
| Edukt | Quinoline-7-carboxylic acid | HCID 599475 | — |
| Produkt | N-(1-Azabicyclo[2.2.2]oct-3-yl)-7-quinolinecarboxamide hydrochloride | HCID 69249623 | 71,1% |
Reaktionsschritte
Prepared in analogy to the method for Example 1 starting from 183 mg of quinoline-7-carboxylic acid (Seibert et al. J. Am. Chem. Soc. 1946, 68, 2721) and 200 mg of 3-aminoquinuclidine dihydrochloride. 227 mg (71% yield) of the hydrochloride were obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07256288B2 |
| Quelldatensatz | uspto-grants-2007_08 |
| ORD ID | ord-bbedf97ddd5f47c69194e1f8e9fd459c |
| Quellennotiz | uspto-grants-2007_08 |