HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(R,R)-Hydrobenzoin → Piragliatin
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (R,R)-Hydrobenzoin | HCID 853019 | — |
| Edukt | 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((S)-3-oxo-cyclopentyl)-N-pyrazin-2-yl-propionamide | HCID 58697917 | — |
| Produkt | Piragliatin | HCID 10432339 | — |
Reaktionsschritte
2(R)-(3-Chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-N-pyrazin-2-yl-propionamide was prepared in a similar manner as 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((S)-3-oxo-cyclopentyl)-N-pyrazin-2-yl-propionamide (Example 47) starting with (R,R)-hydrobenzoin (Wang, Z.-M.; Sharpless, K. B. J. Org. Chem. 1994, 59, 8302).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07259166B2 |
| Quelldatensatz | uspto-grants-2007_08 |
| ORD ID | ord-849465014b514ffbbcd5c0e5468788cb |
| Quellennotiz | uspto-grants-2007_08 |