4-(Methylthio)aniline → N-(4-difluoromethoxybenzylidene)-4-methylthioaniline
Reaktionsgleichung
[F:1][CH:2]([F:12])[O:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1.[CH3:13][S:14][C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=1>>[F:1][CH:2]([F:12])[O:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[N:19][C:18]2[CH:20]=[CH:21][C:15]([S:14][CH3:13])=[CH:16][CH:17]=2)=[CH:6][CH:5]=1Komponenten
3
Versuchsvorschrift
Following a procedure similar to that described in Example 1(i), but using 4-difluoromethoxybenzaldehyde and 4-methylthioaniline as starting materials, N-(4-difluoromethoxybenzylidene)-4-methylthioaniline was obtained in a yield of 91%. This aniline compound and trimethylsilyl cyanide were then reacted together in a similar manner to that described in Example 1(ii), to give the title compound as a slightly yellow powder (yield 80%).
Quellen und Nachweise
- ORD-Eintrag
- ord-ab7bb03df30745508dffe4180a92fe44
- Quelldatensatz
- uspto-grants-2006_12