Nitromethane → 5-Nitro-2-pentanone

HRID 857441Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 857441
[CH:1]([C:3]([CH3:5])=[O:4])=[CH2:2].[N+:6]([CH3:9])([O-:8])=[O:7].[F-].[K+]>C1COCC1>[N+:6]([CH2:9][CH2:2][CH2:1][C:3](=[O:4])[CH3:5])([O-:8])=[O:7]

Komponenten

5

Edukt 3

HCID 6375NitromethaneHCID 6570Methyl vinyl ketoneHCID 522689Potassium Fluoride

Produkt 1

HCID 42950035-Nitro-2-pentanoneAusbeute 93,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

Methyl vinyl ketone (4.17 ml, 0.05 moles), nitromethane (24.4 ml, 0.45 moles) and THF (250 ml) were mixed and stirred together under nitrogen. Potassium fluoride on alumina (10 g) was added and the mixture stirred for 2 hours at ambient temperature. The reaction was filtered and the filtrate was evaporated to give crude 5-nitro-2-pentanone as a pale yellow oil (6.11 g, 93%).

Aufarbeitung

  1. stirringthe mixture stirred for 2 hours at ambient temperature
  2. filtrationThe reaction was filtered
  3. customthe filtrate was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-4850c597e41e47429cd877545da0ffbf
Quelldatensatz
uspto-grants-2006_12
Patentnummer
US07145014B2

Notizen zur Reaktion

Wird geladen…