N,N-Dimethylethylenediamine → Sulfanilamide, N(sup 1)-(2-(dimethylamino)ethyl)-

HRID 858309Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 858309
[S:1](F)(=[O:10])([C:3]1[CH:8]=[CH:7][C:6]([NH2:9])=[CH:5][CH:4]=1)=[O:2].[CH3:12][N:13]([CH3:17])[CH2:14][CH2:15][NH2:16]>C(OCC)(=O)C>[CH3:12][N:13]([CH3:17])[CH2:14][CH2:15][NH:16][S:1](=[O:10])([C:3]1[CH:8]=[CH:7][C:6]([NH2:9])=[CH:5][CH:4]=1)=[O:2]

Komponenten

4

Edukt 2

HCID 66053N,N-DimethylethylenediamineHCID 668234-Aminobenzenesulfonyl fluoride

Produkt 1

HCID 203438Sulfanilamide, N(sup 1)-(2-(dimethylamino)ethyl)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

5.26 g sulphanilic acid fluoride and 16.5 ml of N,N-dimethyl-ethylenediamine are stirred for 4 hours at 100° C., then dissolved in ethyl acetate and extracted three times with saline solution. The residue obtained by evaporation of the organic phase is crystallised from diethyl ether and dried at 60° C.

Aufarbeitung

  1. extractionextracted three times with saline solution
  2. customThe residue obtained by evaporation of the organic phase
  3. customis crystallised from diethyl ether
  4. customdried at 60° C.

Quellen und Nachweise

ORD-Eintrag
ord-f12b51a137e64041950a6ea3ba2fd9c3
Quelldatensatz
uspto-grants-2006_12
Patentnummer
US07148249B2

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