Stannous chloride dihydrate → (3-Amino-4'-cyano-biphenyl-4-yl)-carbamic acid tert.-butyl ester

HRID 859336Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 859336
[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]#[N:21])=[CH:16][CH:15]=2)=[CH:10][C:9]=1[N+:22]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]#[N:21])=[CH:16][CH:15]=2)=[CH:10][C:9]=1[NH2:22])([CH3:4])([CH3:2])[CH3:3]

Komponenten

3

Edukt 2

HCID 61436Stannous chloride dihydrateHCID 69592863(4'-Cyano-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

Produkt 1

HCID 69592808(3-Amino-4'-cyano-biphenyl-4-yl)-carbamic acid tert.-butyl ester

Versuchsvorschrift

Prepared from (4′-cyano-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example C13) by reduction with SnCl2.2H2O according to the general procedure G (method b). Obtained as a yellow solid (360 mg).

Quellen und Nachweise

ORD-Eintrag
ord-4c692c09abb44318b3e2deab1187b9a7
Quelldatensatz
uspto-grants-2006_12
Patentnummer
US07151098B2

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