Potassium Hydroxide → HCID 19418871, Verbindung

Reaktionsgleichung

[Br:1][C:2]1[C:3]([O:15][CH3:16])=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([C:11]([O:13]C)=[O:12])=[CH:7]2.[OH-].[K+]>>[Br:1][C:2]1[C:3]([O:15][CH3:16])=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([C:11]([OH:13])=[O:12])=[CH:7]2

Komponenten

Edukt 2

HCID 14797Potassium Hydroxide

HCID 16726759Methyl 7-bromo-6-methoxy-1H-indole-2-carboxylate

Produkt 1

HCID 19418871HCID 19418871, Verbindung

Versuchsvorschrift

Following the general procedure of PREPARATION 63 and making non-critical variations but starting with methyl 7-bromo-6-methoxyindole carboxylate (PREPARATION 81, 0.36 g) and potassium hydroxide (0.11 g), the title compound is obtained, NMR (300 MHz, CD3OD) 7.58, 7.20, 6.96 and 3.93 δ.

Aufarbeitung

customthe general procedure of PREPARATION 63

Quellen und Nachweise

ORD-Eintrag: ord-278a6ce31b3c47f389071bfab420b31d
Quelldatensatz: uspto-grants-1996_10
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05563142

Notizen zur Reaktion

Wird geladen…