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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 8645Erstellt: 23. Oktober 2026

Potassium Carbonate → (4-Fluoro-benzyl)-[3-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-propyl]-amine

https://huagongshe.com/de/reaction/8645

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPotassium CarbonateHCID 11430—
Edukt4-FluorobenzylamineHCID 67326—
Edukt3-[3-(3-Chloro-propoxy)-phenyl]-thieno[2,3-d]isoxazoleHCID 21983556—
Edukt3-[3-(3-Bromo-propoxy)phenyl]-thieno[2,3-d]isoxazoleHCID 21983559—
Produkt(4-Fluoro-benzyl)-[3-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-propyl]-amineHCID 2198355894%

Reaktionsschritte

The title compound is prepared from a mixture of 3-[3-(3-bromo-propoxy)-phenyl]-thieno[2,3-d]isoxazole, 3-[(3-(3-chloro-propoxy)-phenyl]-thieno[2,3-d]isoxazole, 4-fluorobenzylamine and potassium carbonate essentially as described above in example 4. Combine the appropriate fractions and concentrate to give the title compound (0.36 g, 94% Yield) as an oil. Purity by LC/MS (APCI)=100% area, [M+H]+=383 m/e.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07091199B1
Quelldatensatzuspto-grants-2006_08
ORD IDord-598260d8b1be4001a4fe9d3ea45a3d59
Quellennotizuspto-grants-2006_08