HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Thionyl Chloride → 1-Benzyl-3-(chloromethyl)pyrrolidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | (1-Benzylpyrrolidin-3-yl)methanol | HCID 5176654 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | 1-Benzyl-3-(chloromethyl)pyrrolidine | HCID 12364518 | — |
Reaktionsschritte
To a refluxing solution of 15.3 g (0.08 mole) (3RS)-1-benzyl-3-hydroxymethyl pyrrolidine in 220 ml CHCl3 was slowly added a solution of 330 ml thionyl chloride in 60 ml CHCl3, and the reflux was continued for one hour. The mixture was evaporated and the residue was dissolved in water.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05723444 |
| Quelldatensatz | uspto-grants-1998_03 |
| ORD ID | ord-1537debbdfcd4c9fb2d97af472b6fc7c |
| Quellennotiz | uspto-grants-1998_03 |