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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 8650Erstellt: 23. Oktober 2026

Potassium Carbonate → Pyridin-3-ylmethyl-[3-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-propyl]-amine

https://huagongshe.com/de/reaction/8650

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPotassium CarbonateHCID 11430—
Edukt3-PyridinemethanamineHCID 31018—
Edukt3-[3-(3-Chloro-propoxy)-phenyl]-thieno[2,3-d]isoxazoleHCID 21983556—
Edukt3-[3-(3-Bromo-propoxy)phenyl]-thieno[2,3-d]isoxazoleHCID 21983559—
ProduktPyridin-3-ylmethyl-[3-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-propyl]-amineHCID 986393277%

Reaktionsschritte

The title compound is prepared from a mixture of 3-[3-(3-bromo-propoxy)-phenyl]-thieno[2,3-d]isoxazole, 3-[3-(3-chloro-propoxy)-phenyl]-thieno[2,3-d]isoxazole, 3-(aminomethyl)pyridine and potassium carbonate essentially as described above in example 4. Combine the appropriate fractions and concentrate to give the title compound (0.28 g, 77% Yield) as and oil. Purity by LC/MS (APCI)=98% area, [M+H]+=366 m/e.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07091199B1
Quelldatensatzuspto-grants-2006_08
ORD IDord-b0e631025f7e4cd3bcc06cf3c21e7e9a
Quellennotizuspto-grants-2006_08