N-methyl-2-pyrrolidone → N,N'-bis(phthalimido)oxamide N-methyl-2-pyrrolidone

HRID 866527

Reaktionsgleichung

Reaktionsgleichung von HRID 866527
[C:1]1(=[O:28])[N:5]([NH:6][C:7]([C:9]([NH:11][N:12]2[C:16](=[O:17])[C:15]3=[CH:18][CH:19]=[CH:20][CH:21]=[C:14]3[C:13]2=[O:22])=[O:10])=[O:8])[C:4](=[O:23])[C:3]2=[CH:24][CH:25]=[CH:26][CH:27]=[C:2]12.[CH3:29][N:30]1[CH2:34][CH2:33][CH2:32][C:31]1=[O:35]>C1(C)C=CC=CC=1>[C:13]1(=[O:22])[N:12]([NH:11][C:9]([C:7]([NH:6][N:5]2[C:1](=[O:28])[C:2]3=[CH:27][CH:26]=[CH:25][CH:24]=[C:3]3[C:4]2=[O:23])=[O:8])=[O:10])[C:16](=[O:17])[C:15]2=[CH:18][CH:19]=[CH:20][CH:21]=[C:14]12.[CH3:29][N:30]1[CH2:34][CH2:33][CH2:32][C:31]1=[O:35]

Komponenten

4

Edukt 2

HCID 13387N-methyl-2-pyrrolidoneHCID 113193Ethanediamide, N1,N2-bis(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-

Produkt 1

HCID 70604243N,N'-bis(phthalimido)oxamide N-methyl-2-pyrrolidoneAusbeute 96 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Reaktionsbedingungen

Temperatur
70 °C

Versuchsvorschrift

In an alternate method, one mole N,N'-bis(phthalimido)-oxamide (378 g.) prepared according to the method of Example 1 and excess N-methyl-2-pyrrolidone (198 g.) in two liters toluene were heated at 70° C. After cooling, the complex was filtered, washed and dried at 50° C. N,N'-bis(phthalimido)oxamide-N-methyl-2-pyrrolidone 1:2 complex was obtained in 96% yield.

Aufarbeitung

  1. temperatureAfter cooling
  2. filtrationthe complex was filtered
  3. washwashed
  4. customdried at 50° C

Quellen und Nachweise

ORD-Eintrag
ord-cf7f4ac957164e83b707615ff16f8fa0
Quelldatensatz
uspto-grants-1978_07
Patentnummer
US04100132

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