3,4-Dichloroaniline → 2,3-Dichloro-N-[(3,4-dichlorophenyl)carbamoyl]propanamide

HRID 866775Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 866775
[Cl:1][CH:2]([CH2:8][Cl:9])[C:3]([N:5]=[C:6]=[O:7])=[O:4].[Cl:10][C:11]1[CH:12]=[C:13]([CH:15]=[CH:16][C:17]=1[Cl:18])[NH2:14]>C1C=CC=CC=1>[Cl:10][C:11]1[CH:12]=[C:13]([NH:14][C:6]([NH:5][C:3](=[O:4])[CH:2]([Cl:1])[CH2:8][Cl:9])=[O:7])[CH:15]=[CH:16][C:17]=1[Cl:18]

Komponenten

4

Edukt 2

HCID 72573,4-DichloroanilineHCID 203185352,3-Dichloropropanoyl isocyanate

Produkt 1

HCID 203185612,3-Dichloro-N-[(3,4-dichlorophenyl)carbamoyl]propanamideAusbeute 76 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel2×

Reaktionsbedingungen

Temperatur
20 °C

Versuchsvorschrift

A solution of 17.0 g (0.1 mole) of 2,3-dichloropropionyl isocyanate in 50 ml of wash benzine was added dropwise to a solution of 16.0 g (0.1 mole) of 3,4-dichloroaniline in 150 ml of dry benzene at 0° to 5° C, while cooling. In the course thereof, the reaction product crystallized out. The mixture was stirred for a further hour at 20° C and was filtered, and the product was washed with petroleum ether and dried. 25 g of N-(3,4-dichlorophenyl)-N'-(2,3-dichloropropionyl)-urea of melting point 145° to 148° C, with decomposition, were obtained. The yield was 76% of theory.

Aufarbeitung

  1. temperaturewhile cooling
  2. customIn the course thereof, the reaction product crystallized out
  3. filtrationwas filtered
  4. washthe product was washed with petroleum ether
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-e0465ca36bea474caabec70f7cd52b7b
Quelldatensatz
uspto-grants-1978_07
Patentnummer
US04101575

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