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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 8684Erstellt: 23. Oktober 2026

1-Phenylpiperazine → 3-{3-[2-(4-Phenyl-piperazin-1-yl)-ethoxy]-phenyl}-thieno[2,3-d]isoxazole

https://huagongshe.com/de/reaction/8684

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-PhenylpiperazineHCID 7096—
EduktPotassium CarbonateHCID 11430—
Edukt3-[3-(2-Bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazoleHCID 21983582—
Produkt3-{3-[2-(4-Phenyl-piperazin-1-yl)-ethoxy]-phenyl}-thieno[2,3-d]isoxazoleHCID 2198359566%

Reaktionsschritte

The title compound is prepared from 3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, and N-phenylpiperazine essentially as described in example 27 except that the freebase is dried to give the title compound (330 mg, 66%). Mp=91–93° C. Microanalysis (C, H, N) is consistent with the final compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07091199B1
Quelldatensatzuspto-grants-2006_08
ORD IDord-7a208bef3d67408193e3c036ee51db44
Quellennotizuspto-grants-2006_08