[NH:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[C:12]([O:14][CH3:15])=[O:13])[C:4](=[O:5])[C:2]1=[O:3].Cl.[CH:17]([N:20]([CH:24]([CH3:26])[CH3:25])[CH2:21][CH2:22]Cl)([CH3:19])[CH3:18]>>[CH:17]([N:20]([CH:24]([CH3:26])[CH3:25])[CH2:21][CH2:22][N:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[C:12]([O:14][CH3:15])=[O:13])[C:4](=[O:5])[C:2]1=[O:3])([CH3:19])[CH3:18]By using methyl 7-isatincarboxylate and 2-diisopropylaminoethyl chloride hydrochloride, a method analogous to that described in Reference Example 7 was carried out to obtain methyl 1-(2-diisopropylaminoethyl)-7-isatincarboxylate in an oil (yield: 94.6%).
Wird geladen…