Hydrochloric Acid → HCID 66642852, Verbindung
Reaktionsgleichung
[NH2:1][CH:2]1[CH2:7][CH2:6][C:5]([NH:9]C(=O)OC(C)(C)C)([CH3:8])[CH2:4][CH2:3]1.C(O)C.[ClH:20]>C(OCC)(=O)C>[ClH:20].[ClH:20].[CH3:8][C:5]1([NH2:9])[CH2:6][CH2:7][CH:2]([NH2:1])[CH2:3][CH2:4]1Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a mixture of tert-butyl (4-amino-1-methylcyclohexyl)carbamate (Preparation Example 399) (3.73 g) and ethanol (30 mL), 4M hydrogen chloride in ethyl acetate (30 mL) was added under ice cooling and stirred at room temperature for 20 hours. The precipitated solid was collected by filtration and washed with ethyl acetate to give 1-methylcyclohexane-1,4-diamine dihydrochloride (2.10 g) as a white solid.
Aufarbeitung
- additionwas added under ice cooling
- filtrationThe precipitated solid was collected by filtration
- washwashed with ethyl acetate
Quellen und Nachweise
- ORD-Eintrag
- ord-a3defbda903c4b33adc2cbe920d52327
- Quelldatensatz
- uspto-grants-2015_03
- Patentnummer
- US08969336B2
Notizen zur Reaktion
Wird geladen…