2-(azetidin-1-yl)-1H-benzo[d]imidazole → (E)-2-(8-{[2-(azetidin-1-yl)-1H-benzo[d]imidazol-1-yl]methyl}-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene)propanenitrile

Beteiligte Stoffe

Reaktionsschritte

[step 2] Using 2-(azetidin-1-yl)-1H-benzo[d]imidazole (40 mg, 0.23 mmol) obtained in step 1 and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (84 mg, 0.24 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (61 mg, 59%) was obtained.

Herkunft & Nachweise