Potassium Hydroxide → Potassium 5-chloro-2-fluoro-4-nitrophenolate

Reaktionsgleichung

[Cl:1][C:2]1[CH:7]=[C:6](F)[C:5]([F:9])=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11].[OH-:13].[K+:14]>>[Cl:1][C:2]1[C:3]([N+:10]([O-:12])=[O:11])=[CH:4][C:5]([F:9])=[C:6]([O-:13])[CH:7]=1.[K+:14]

Komponenten

Edukt 2

HCID 14797Potassium Hydroxide

HCID 101303301-Chloro-4,5-difluoro-2-nitrobenzene

Produkt 1

HCID 90016791Potassium 5-chloro-2-fluoro-4-nitrophenolate

Versuchsvorschrift

A mixture of 1-chloro-4,5-difluoro-2-nitrobenzene (5.12 g, 26.5 mmol) and 15% aqueous KOH (19.9 g) solution was stirred at reflux for 3 hours, then cooled to rt, and filtered to give the title compound as a yellow crystalloid (5.67 g, 93.3%).

Aufarbeitung

temperatureat reflux for 3 hours
filtrationfiltered

Quellen und Nachweise

ORD-Eintrag: ord-d3f7b68050cd4963b12898670a0a47cb
Quelldatensatz: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08969388B1

Notizen zur Reaktion

Wird geladen…