HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → Octanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Levofloxacin | HCID 149096 | — |
| Edukt | Sodium octanoate | HCID 23664772 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Octanoate | HCID 119389 | — |
| Produkt | Levofloxacin | HCID 149096 | — |
Reaktionsschritte
One gram of sodium octanoate and one gram of levofloxacin were dissolved in 100 ml water. The pH was slowly adjusted to 6.0 by the addition of 1 M HCl. As the pH decreased, levofloxacin became protonated formed an insoluble HIP with the negatively charged octanoate. The precipitate was gathered by filtration to remove excess levofloxacin, dissolved sodium octanoate/octanoic acid, and salt. The sample was lyophilized overnight.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08974814B2 |
| Quelldatensatz | uspto-grants-2015_03 |
| ORD ID | ord-3c6fcf879372438aa17574c118390070 |
| Quellennotiz | uspto-grants-2015_03 |