4-Iodo-1-methyl-1H-pyrazole-5-carboxylic acid → 4-(6-cyanopyridin-2-yl)-1-methyl-1H-pyrazole-5-carboxylic acid
Reaktionsgleichung
Br[C:2]1[N:7]=[C:6]([C:8]#[N:9])[CH:5]=[CH:4][CH:3]=1.I[C:11]1[CH:12]=[N:13][N:14]([CH3:19])[C:15]=1[C:16]([OH:18])=[O:17]>>[C:8]([C:6]1[N:7]=[C:2]([C:11]2[CH:12]=[N:13][N:14]([CH3:19])[C:15]=2[C:16]([OH:18])=[O:17])[CH:3]=[CH:4][CH:5]=1)#[N:9]Komponenten
3
Versuchsvorschrift
Using 6-bromopicolinonitrile (0.73 g) and 4-iodo-1-methyl-1H-pyrazole-5-carboxylic acid (1 g), the title compound (4.7 mg) was obtained in the form of a colorless solid by the same method as that of (Example 3.22) <Step 1> or a method equivalent thereto.
Quellen und Nachweise
- ORD-Eintrag
- ord-fc4a3a0cc1184d409db48f2798a34418
- Quelldatensatz
- uspto-grants-2015_03
- Patentnummer
- US08980889B2
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