Trifluoroacetate → HCID 86673535, Verbindung

HRID 874983Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 874983
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]([CH:13]3[CH2:18][CH2:17][CH2:16][N:15](C(OC(C)(C)C)=O)[CH2:14]3)[S:11][CH:12]=2)=[CH:4][CH:3]=1.[F:26][C:27]([F:32])([F:31])[C:28]([O-:30])=[O:29]>>[OH:30][C:28]([C:27]([F:32])([F:31])[F:26])=[O:29].[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]([CH:13]3[CH2:18][CH2:17][CH2:16][NH:15][CH2:14]3)[S:11][CH:12]=2)=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 84468TrifluoroacetateHCID 69935474HCID 69935474, Verbindung

Produkt 1

HCID 86673535HCID 86673535, Verbindung

Versuchsvorschrift

This compound was synthesized from tert-butyl 3-(4-(4-fluorophenyl)thiazol-2-yl)piperidine-1-carboxylate as described for example 46 step 4 (80 mg, crude) as a trifluoroacetate salt and it was carried through without further purification. MS (ESI) m/z: Calculated for C14H15FN2S: 262.09. found: 263.0 (M+H)+

Aufarbeitung

  1. customwas carried through without further purification

Quellen und Nachweise

ORD-Eintrag
ord-d7275e3393a64a5f98fee4f3d9c9ffeb
Quelldatensatz
uspto-grants-2015_03
Patentnummer
US08981084B2

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