Ethylene → HCID 178476818, Verbindung

HRID 875275

Reaktionsgleichung

Reaktionsgleichung von HRID 875275
C[P:2]([OH:11])([CH2:4][CH2:5][C@H:6](N)C(O)=O)=[O:3].P(Cl)(Cl)Cl.[Cl-:16].[Cl-].[Cl-].[Cl-].[Al+3].[CH2:21]=[CH2:22]>C(O)C>[Cl:16][CH2:6][CH2:5][CH2:4][PH:2](=[O:3])[O:11][CH2:21][CH3:22]

Komponenten

6

Edukt 4

HCID 6325EthyleneHCID 24387Phosphorus trichlorideHCID 91619PhosphinothricinHCID 25114082Aluminum tetrachloride

Produkt 1

HCID 178476818HCID 178476818, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Another process of producing phosphinothricin generally comprises converting phosphorus trichloride to an adduct of methylphosphonous trichloride and aluminum tetrachloride (i.e., CH3PCl3.AlCl4). The adduct is reacted with ethylene to form an intermediate adduct, which is then reacted with ethanol to form ethyl 1-(2-chloroethyl)-methylphosphinate. This compound is reacted with potassium hydroxide and ethanol to prepare an ethyl vinylphosphinate precursor. The ethyl vinylphosphinate precursor is subjected to hydroformylation-aminocarbonylation, followed by hydrolysis of the hydroformylation-aminocarbonylation product in the presence of hydrochloric acid to produce phosphinothricin.

Aufarbeitung

  1. customto form an intermediate adduct, which

Quellen und Nachweise

ORD-Eintrag
ord-402523d6d8d74830b45d44bbad92c16d
Quelldatensatz
uspto-grants-2015_03
Patentnummer
US08981142B2

Verknüpfte Notizen

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