HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Bromopyridine-2-carboxylic acid → 5-Bromo-N-[1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]pyridine-2-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Bromopyridine-2-carboxylic acid | HCID 608544 | — |
| Edukt | 1-(Cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate | HCID 66701344 | — |
| Produkt | 5-Bromo-N-[1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidin-3-yl]pyridine-2-carboxamide | HCID 66761509 | — |
Reaktionsschritte
139 mg (0.34 mmol) of 1-(cyclopentylcarbonyl)-5-(4-ethylphenyl)piperidine-3-amine trifluoroacetate (Example 8A) and 68 mg (0.34 mmol, 1.0 eq.) of 5-bromopyridine-2-carboxylic acid were reacted according to General Method 1. Yield: 75 mg (44% of theory)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08987248B2 |
| Quelldatensatz | uspto-grants-2015_03 |
| ORD ID | ord-18accb3768bb478392ef44bd3b7fec4b |
| Quellennotiz | uspto-grants-2015_03 |