Morpholine → 4-(6-Chloropyrimidin-4-yl)morpholine

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

45.0 g (302.1 mmol) 4,6-dichloropyrimidine are initially introduced into 450 ml water. 26.3 g (302.1 mmol) morpholine are added and the mixture is stirred at 90° C. for 16 h. Thereafter, it is cooled to 0° C. and the precipitate formed is filtered off. The precipitate is washed once with 50 ml water and dried in air.

Herkunft & Nachweise