HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) → N-Methyl-N-[4-(2-trifluoromethoxy-phenyl)-pyridin-3-yl]-3,5-bis-trifluoromethyl-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) | HCID 2777204 | — |
| Edukt | N-(4-bromo-pyridin-3-yl)-N-methyl-3,5-bis-trifluoromethyl-benzamide | HCID 86670692 | — |
| Produkt | N-Methyl-N-[4-(2-trifluoromethoxy-phenyl)-pyridin-3-yl]-3,5-bis-trifluoromethyl-benzamide | HCID 88879745 | — |
Reaktionsschritte
The title compound was prepared in analogy to example 25, from N-(4-bromo-pyridin-3-yl)-N-methyl-3,5-bis-trifluoromethyl-benzamide (example 25, intermediate a) and 2-(trifluormethoxy)phenylboronic acid (CAS RN 175676-65-0). Off-white solid (34%). MS (ESI): m/z=509.4 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08987307B2 |
| Quelldatensatz | uspto-grants-2015_03 |
| ORD ID | ord-795d5ef07f8d40aea2e5df2150c6d1c5 |
| Quellennotiz | uspto-grants-2015_03 |