HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,4-Difluoroacetophenone → 1-(2,4-Difluorophenyl)-3-(dimethylamino)prop-2-en-1-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,4-Difluoroacetophenone | HCID 67770 | — |
| Edukt | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Produkt | 1-(2,4-Difluorophenyl)-3-(dimethylamino)prop-2-en-1-one | HCID 5714027 | 82% |
Reaktionsschritte
The title compound was prepared in 82% yield from 1-(2,4-difluorophenyl)ethanone and DMF-DMA according to the procedure for the preparation of Example 12, part A. 1H NMR (400 MHz, CDCl3): δ 2.90 (3H, s), 3.11(3H, s), 5.59-5.62 (1H, m), 6.77-6.83 (1H, m), 6.88-6.93 (m, 1H), 7.75-7.83 (2H, m).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08987461B2 |
| Quelldatensatz | uspto-grants-2015_03 |
| ORD ID | ord-4e62d7f6a9374c81b6e736e580ec4021 |
| Quellennotiz | uspto-grants-2015_03 |