(2-Nitrophenyl)hydrazine → HCID 178517309, Verbindung

HRID 878791

Reaktionsgleichung

Reaktionsgleichung von HRID 878791
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH:7][S:8]([C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[C:14]2=O)(=[O:10])=[O:9].[N+:22]([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[NH:31][NH2:32])([O-:24])=[O:23]>Cl.C(O)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH:7][S:8]([C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[C:14]2=[N:32][NH:31][C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=1[N+:22]([O-:24])=[O:23])(=[O:10])=[O:9]

Komponenten

5

Edukt 2

HCID 3314739(2-Nitrophenyl)hydrazineHCID 59763031HCID 59763031, Verbindung

Produkt 1

HCID 178517309HCID 178517309, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 313Hydrochloric AcidKatalysatorHCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
120 °C

Versuchsvorschrift

A mixture of rpm161 (0.040 g, 0.114 mmol) 2-nitrophenylhydrazine (0.021 g, 0.126 mmol, 1.1 eq) and HCl (aq 4 M, 2 drops) in ethanol (3 mL) was heated in the CEM microwave at 120° C. for 15 min. After cooling to room temperature, pure product rpm168 was collected as an orange precipitate by filtration and dried in vacuo. The pure compound rpm168 was obtained without further purification (0.048 g, 0.099 mmol, 86%). MS (API-ES): m/z 459 (M+NH4)+; HRMS (API-ES) m/z Found: 459.1082 (M+NH4)+.

Aufarbeitung

  1. temperatureAfter cooling to room temperature
  2. filtrationwas collected as an orange precipitate by filtration
  3. customdried in vacuo
  4. customwas obtained without further purification (0.048 g, 0.099 mmol, 86%)

Quellen und Nachweise

ORD-Eintrag
ord-3013d6af1a784f6da467cae0cdc17c3c
Quelldatensatz
uspto-grants-2015_03
Patentnummer
US08987474B2

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