6-Bromo-1-methyl-1H-indazol-3-amine → 6-bromo-1-methyl-3-(4-methylpiperazin-1-yl)-1H-indazole
Reaktionsgleichung
Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH3:11])[N:6]=[C:5]2[N:12]1[CH2:17][CH2:16][N:15]([CH3:18])[CH2:14][CH2:13]1.[Br:19]C1C=C2C(C(N)=NN2C)=CC=1>>[Br:19][C:10]1[CH:9]=[C:8]2[C:4]([C:5]([N:12]3[CH2:17][CH2:16][N:15]([CH3:18])[CH2:14][CH2:13]3)=[N:6][N:7]2[CH3:11])=[CH:3][CH:2]=1Komponenten
3
Versuchsvorschrift
Prepared in a manner similar to 5-bromo-1-methyl-3-(4-methylpiperazin-1-yl)-1H-indazole but using 6-bromo-1-methyl-1H-indazol-3-amine instead of 5-bromo-1-methyl-1H-indazol-3-amine. LCMS-ESI+: calc'd for C13H17BrN4: 309.1, 311.1 (M+H+); Found: 309.2, 311.2 (M+H+).
Quellen und Nachweise
- ORD-Eintrag
- ord-04a6b9ba62a04690911e40f768974253
- Quelldatensatz
- uspto-grants-2015_03