HCID 86700409, Verbindung → HCID 86700408, Verbindung

HRID 879594Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 879594
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]3[CH2:16][NH:15][C:14](=O)[CH2:13][O:12]3)=[CH:8][CH:9]=2)[CH:4]=[N:3]1>C1COCC1>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]3[O:12][CH2:13][CH2:14][NH:15][CH2:16]3)=[CH:8][CH:9]=2)[CH:4]=[N:3]1

Komponenten

3

Edukt 1

HCID 86700409HCID 86700409, Verbindung

Produkt 1

HCID 86700408HCID 86700408, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel2×

Versuchsvorschrift

To a solution of 6-(1-methyl-1H-indazol-5-yl)morpholin-3-one (17.8 mg, 0.077 mmol) in THF was added BH3 in THF (1M, mmol). The resulting mixture was stirred at room temperature for 10 hr. The crude compound was evaporated to dryness and used for the next step without further purification. LCMS-ESI+: calc'd for C12H15N3O: 218.1 (M+H+); found: 218.2 (M+H+).

Aufarbeitung

  1. customThe crude compound was evaporated to dryness
  2. customused for the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-af3458411c5147519def525373ce9cb5
Quelldatensatz
uspto-grants-2015_03
Patentnummer
US08987250B2

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