3-(Cyclopentyloxy)aniline → HCID 136352196, Verbindung

HRID 880104Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 880104
[N:1]1([C:7]2[N:8]=[C:9]([CH2:14][C:15]([O-:17])=O)[NH:10][C:11](=[O:13])[CH:12]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[Na+].[CH:19]1([O:24][C:25]2[CH:26]=[C:27]([CH:29]=[CH:30][CH:31]=2)[NH2:28])[CH2:23][CH2:22][CH2:21][CH2:20]1>>[CH:19]1([O:24][C:25]2[CH:26]=[C:27]([NH:28][C:15](=[O:17])[CH2:14][C:9]3[NH:10][C:11](=[O:13])[CH:12]=[C:7]([N:1]4[CH2:2][CH2:3][O:4][CH2:5][CH2:6]4)[N:8]=3)[CH:29]=[CH:30][CH:31]=2)[CH2:23][CH2:22][CH2:21][CH2:20]1

Komponenten

3

Edukt 2

HCID 167830523-(Cyclopentyloxy)anilineHCID 136041844Sodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetate

Produkt 1

HCID 136352196HCID 136352196, VerbindungAusbeute 67,8 %

Versuchsvorschrift

The product is prepared according to the procedure described in Example 5, using 260 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 354 mg of 3-(cyclopentyloxy)aniline in place of the 2,4-difluoroaniline. 269 mg of N-[3-(cyclopentyloxy)phenyl]-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a white solid, the characteristics of which are the following:

Aufarbeitung

  1. customThe product is prepared

Quellen und Nachweise

ORD-Eintrag
ord-ec857d41e8d547fdac594fa685b96835
Quelldatensatz
uspto-grants-2015_03
Patentnummer
US08993565B2

Notizen zur Reaktion

Wird geladen…