Ethyl 2-(4-bromophenyl)-2-methylpropanoate → 2-Methyl-2-(1,3-thiazol-2-yl)propanoic acid

Reaktionsgleichung

[CH3:1][C:2]([C:9]1[S:10][CH:11]=[CH:12][N:13]=1)([CH3:8])[C:3]([O:5]CC)=[O:4].BrC1C=CC(C(C)(C)C(OCC)=O)=CC=1>>[CH3:8][C:2]([C:9]1[S:10][CH:11]=[CH:12][N:13]=1)([CH3:1])[C:3]([OH:5])=[O:4]

Komponenten

Edukt 2

HCID 11277257Ethyl 2-(4-bromophenyl)-2-methylpropanoate

HCID 21099803Ethyl 2-methyl-2-(thiazol-2-yl)propanoate

Produkt 1

HCID 210997222-Methyl-2-(1,3-thiazol-2-yl)propanoic acid

Versuchsvorschrift

The title compound was prepared according to the method of Example 22B substituting the product of Example 44D for the product of Example 22A.

Quellen und Nachweise

ORD-Eintrag: ord-525a1754c4504b0d8534a1076414aa37
Quelldatensatz: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08993632B2

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