Acetonitrile → 4-Amino-4'-propylazobenzene

Beteiligte Stoffe

Reaktionsschritte

To a solution of the aminoazobenzene (1 eq) and DIPEA (2 eq) in 1:1 MeCN:DMF at 0° C. was added 2-triethylammonium acetic acid chloride chloride8 (1.5 eq) in 1:1 MeCN:DMF and stirred for 15 min, then warmed to ambient temperature and stirred for 1-12 h at which time the solvent was removed in vacuo for purification by reverse phase silica gel chromatography (0.1% formic acid in H2O, gradient up to 50% MeCN: 0.1% formic acid in H2O).

Herkunft & Nachweise