Hydrochloric Acid → (R)-ethyl 3-amino-4-(biphenyl-4-yl)butanoate hydrochloride

Beteiligte Stoffe

Reaktionsschritte

To (R)-ethyl-4-(biphenyl-4-yl)-3-(tert-butoxycarbonylamino)butanoate (300 mg, 0.782 mmol) is added a solution of 4M HCl in 1,4-dioxane (3.92 mL, 15.65 mmol) at room temperature. After stirring for 1 hour, the reaction mixture is concentrated under reduced pressure to give (R)-3-amino-4-biphenyl-4-yl-butyric acid ethyl ester hydrochloride.

Herkunft & Nachweise