HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Rosiglitazone → Pioglitazone, (R)-
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Rosiglitazone | HCID 77999 | — |
| Edukt | (E)-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione | HCID 14211277 | — |
| Produkt | Pioglitazone, (R)- | HCID 29010894 | — |
Reaktionsschritte
Biocatalytic reduction of 5-[1-{4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-phenyl}-meth-(E)-ylidene]-thiazolidine-2,4-dione was investigated using literature procedures described for Rosiglitazone (J. Chem. Soc. Perkin Trans. I, 1994, 3319-3324).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08236786B2 |
| Quelldatensatz | uspto-grants-2012_08 |
| ORD ID | ord-a1d64ffa47914ff0add7c2fa22c7cfca |
| Quellennotiz | uspto-grants-2012_08 |