Methylamine → 1-Isobutyl-3-methylthiourea

HRID 883552

Reaktionsgleichung

Reaktionsgleichung von HRID 883552
[CH3:1][NH2:2].[CH2:3]([N:7]=[C:8]=[S:9])[CH:4]([CH3:6])[CH3:5]>>[CH2:3]([NH:7][C:8]([NH:2][CH3:1])=[S:9])[CH:4]([CH3:6])[CH3:5]

Komponenten

3

Edukt 2

HCID 6329MethylamineHCID 68960Isobutyl isothiocyanate

Produkt 1

HCID 155682431-Isobutyl-3-methylthioureaAusbeute 98,2 %

Versuchsvorschrift

Methylamine (2M in methanol, 20.0 mL, 40.2 mmol) was added dropwise to isobutylisothiocyanate (2.00 mL, 16.5 mmol) during 15 minutes at room temperature. The reaction mixture was heated to reflux for 3.5 h and the solvent was evaporated off to give the title compound (2.37 g, 98%) as a colourless oil.

Aufarbeitung

  1. temperatureThe reaction mixture was heated
  2. temperatureto reflux for 3.5 h
  3. customthe solvent was evaporated off

Quellen und Nachweise

ORD-Eintrag
ord-a009c415bc374a209f29a2f4261b069c
Quelldatensatz
uspto-grants-2012_08
Patentnummer
US08236951B2

Verknüpfte Notizen

Wird geladen…