Methylamine → 1-Isobutyl-3-methylthiourea
Reaktionsgleichung
[CH3:1][NH2:2].[CH2:3]([N:7]=[C:8]=[S:9])[CH:4]([CH3:6])[CH3:5]>>[CH2:3]([NH:7][C:8]([NH:2][CH3:1])=[S:9])[CH:4]([CH3:6])[CH3:5]Komponenten
3
Versuchsvorschrift
Methylamine (2M in methanol, 20.0 mL, 40.2 mmol) was added dropwise to isobutylisothiocyanate (2.00 mL, 16.5 mmol) during 15 minutes at room temperature. The reaction mixture was heated to reflux for 3.5 h and the solvent was evaporated off to give the title compound (2.37 g, 98%) as a colourless oil.
Aufarbeitung
- temperatureThe reaction mixture was heated
- temperatureto reflux for 3.5 h
- customthe solvent was evaporated off
Quellen und Nachweise
- ORD-Eintrag
- ord-a009c415bc374a209f29a2f4261b069c
- Quelldatensatz
- uspto-grants-2012_08
- Patentnummer
- US08236951B2
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