Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 883644Erstellt: 27. Oktober 2026

Potassium Cyanide → methyl cyano[3-cyano-2-oxo-5-(trifluoromethoxy)-2,3-dihydro-1H-indol-3-yl]acetate

https://huagongshe.com/reaction/883644

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPotassium CyanideHCID 9032—
Eduktmethyl (2Z)-cyano[2-oxo-5-(trifluoromethoxy)-1,2-dihydro-3H-indol-3-ylidene]acetateHCID 67424559—
Produktmethyl cyano[3-cyano-2-oxo-5-(trifluoromethoxy)-2,3-dihydro-1H-indol-3-yl]acetateHCID 6742538190%

Reaktionsschritte

Following the general method as outlined for Intermediate 5, starting from methyl (2Z)-cyano[2-oxo-5-(trifluoromethoxy)-1,2-dihydro-3H-indol-3-ylidene]acetate (intermediate 3) and potassium cyanide, the title compound was isolated, after evaporation, as a pale brown solid in 90% yield. This was a mixture of diastereomers.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08236963B2
Quelldatensatzuspto-grants-2012_08
ORD IDord-f3d4a8b30f0a4d6894bd12c0f1f01b3b
Quellennotizuspto-grants-2012_08