HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phosphorus oxychloride → Ethyl 4-chloro-7-methyl-1,8-naphthyridine-3-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phosphorus oxychloride | HCID 24813 | — |
| Edukt | Ethyl 7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate | HCID 5373687 | — |
| Produkt | Ethyl 4-chloro-7-methyl-1,8-naphthyridine-3-carboxylate | HCID 10562672 | 57% |
Reaktionsschritte
The product from Example 7b (1.0 g, 4.30 mmol) was reacted with 12 mL of POCl3 for 4 h following the procedure from Example 7d giving the title compound as a brownish-pink solid (619 mg, 57%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08236950B2 |
| Quelldatensatz | uspto-grants-2012_08 |
| ORD ID | ord-f7d5db8c756f4e4f9f8aa34de6741ab5 |
| Quellennotiz | uspto-grants-2012_08 |