Dimethylformamide dimethyl acetal → HCID 66808327, Verbindung

HRID 883980Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 883980
[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[CH:6][C:5]([C:10]#[N:11])=[C:4]([CH3:12])[N:3]=1.CO[CH:15](OC)[N:16]([CH3:18])[CH3:17]>C1(C)C=CC=CC=1>[C:8]([C:7]1[C:2]([N:1]=[CH:15][N:16]([CH3:18])[CH3:17])=[N:3][C:4]([CH3:12])=[C:5]([C:10]#[N:11])[CH:6]=1)#[N:9]

Komponenten

4

Edukt 2

HCID 78373Dimethylformamide dimethyl acetalHCID 27867262-Amino-6-methylpyridine-3,5-dicarbonitrile

Produkt 1

HCID 66808327HCID 66808327, VerbindungAusbeute 94 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

A solution of 2-Amino-6-methyl-pyridine-3,5-dicarbonitrile (0.158 g, 1.0 mmol) and N,N-Dimethylformamide dimethyl acetal (0.119 g, 1.0 mmol) in toluene (10 mL) was heated at reflux for 6 hours. After cooling to room temperature, the solution was concentrated under vacuum to provide the title compound as a brown solid (0.2 g, 94%).

Aufarbeitung

  1. temperatureat reflux for 6 hours
  2. concentrationthe solution was concentrated under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-85a5cbe9840641139fb5fac0b6aab6d5
Quelldatensatz
uspto-grants-2012_08
Patentnummer
US08236950B2

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