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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 884984Erstellt: 27. Oktober 2026

HCID 178418361, Verbindung → 3-Amino-5-(trifluoromethyl)-1,2-dihydropyridin-2-one

https://huagongshe.com/reaction/884984

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHCID 178418361HCID 178418361—
EduktHCID 178526653HCID 178526653—
KatalysatorPalladiumHCID 23938—
LösungsmittelMethanolHCID 887—
Produkt3-Amino-5-(trifluoromethyl)-1,2-dihydropyridin-2-oneHCID 231578799,3%

Reaktionsschritte

A mixture of 3.13 g of 2-hydroxy-3-nitro-5-trifluoromethylpyridine, 40 ml of methanol and 0.85 g of 5% palladium on carbon was stirred under about one atmosphere of hydrogen at room temperature for two hours. The reaction mixture was filtered through Celite™. The filtrate was concentrated under reduced pressure to give 2.66 g of 3-amino-2-hydroxy-5-trifluoromethylpyridine.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08242133B2
Quelldatensatzuspto-grants-2012_08
ORD IDord-c5aa95dbbd68471cb46461c65ab3c1d7
Quellennotizuspto-grants-2012_08