HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 178418361, Verbindung → 3-Amino-5-(trifluoromethyl)-1,2-dihydropyridin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | HCID 178418361 | HCID 178418361 | — |
| Edukt | HCID 178526653 | HCID 178526653 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 3-Amino-5-(trifluoromethyl)-1,2-dihydropyridin-2-one | HCID 2315787 | 99,3% |
Reaktionsschritte
A mixture of 3.13 g of 2-hydroxy-3-nitro-5-trifluoromethylpyridine, 40 ml of methanol and 0.85 g of 5% palladium on carbon was stirred under about one atmosphere of hydrogen at room temperature for two hours. The reaction mixture was filtered through Celite™. The filtrate was concentrated under reduced pressure to give 2.66 g of 3-amino-2-hydroxy-5-trifluoromethylpyridine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08242133B2 |
| Quelldatensatz | uspto-grants-2012_08 |
| ORD ID | ord-c5aa95dbbd68471cb46461c65ab3c1d7 |
| Quellennotiz | uspto-grants-2012_08 |