HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Baclofen → 4-(4-Chlorophenyl)-2-pyrrolidinone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Baclofen | HCID 2284 | — |
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 4-(4-Chlorophenyl)-2-pyrrolidinone | HCID 185490 | — |
Reaktionsschritte
To Baclofen (1.0 g, 4.7 mmol) in CH2Cl2 (20 mL) was added thionyl chloride (0.38 mL, 5.2 mmol), and the reaction was stirred for 10 minutes. Diisopropylethylamine (1.5 mL) was added, and the mixture was worked-up to give the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08242145B2 |
| Quelldatensatz | uspto-grants-2012_08 |
| ORD ID | ord-417fc5766c154604aeaddd8638a0c2ee |
| Quellennotiz | uspto-grants-2012_08 |