4,4-Difluoro-4-phenylbutan-1-ol → {4-[(6-Bromohexyl)oxy]-1,1-difluorobutyl}benzene
Reaktionsgleichung
[F:1][C:2]([F:13])([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH2:3][CH2:4][CH2:5][OH:6].[Br:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]OCC(F)(F)CCC1C=CC=CC=1>>[Br:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][O:6][CH2:5][CH2:4][CH2:3][C:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([F:13])[F:1]Komponenten
3
Versuchsvorschrift
Obtained from Intermediate 22 (0.6 g, 3.22 mmol) by the procedure described in Intermediate 3. The title compound was obtained (1.98 g, 63% purity) as oil.
Quellen und Nachweise
- ORD-Eintrag
- ord-ec1890c5335c4c49a41ef52d0982cace
- Quelldatensatz
- uspto-grants-2012_08
- Patentnummer
- US08242177B2
Notizen zur Reaktion
Wird geladen…