Piperidine, 1-methyl,4-methylene- → N-[3-(1-Methyl-piperidin-4-ylmethyl)-5-trifluoromethyl-phenyl]-acetamide

HRID 888087

Reaktionsgleichung

Reaktionsgleichung von HRID 888087
[CH3:1][N:2]1[CH2:7][CH2:6][C:5](=[CH2:8])[CH2:4][CH2:3]1.N1(CCC[C:18]2[CH:19]=[C:20]([NH:28][C:29](=[O:31])[CH3:30])[CH:21]=[C:22]([C:24]([F:27])([F:26])[F:25])[CH:23]=2)CCCCC1>>[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]([CH2:8][C:18]2[CH:19]=[C:20]([NH:28][C:29](=[O:31])[CH3:30])[CH:21]=[C:22]([C:24]([F:25])([F:26])[F:27])[CH:23]=2)[CH2:4][CH2:3]1

Komponenten

3

Edukt 2

HCID 139537Piperidine, 1-methyl,4-methylene-HCID 21959446N-[3-(3-Piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide

Produkt 1

HCID 69435668N-[3-(1-Methyl-piperidin-4-ylmethyl)-5-trifluoromethyl-phenyl]-acetamide

Versuchsvorschrift

N-[3-(1-Methyl-piperidin-4-ylmethyl)-5-trifluoromethyl-phenyl]-acetamide was prepared from 1-Methyl-4-methylene-piperidine similar to that described in the preparation of N-[3-(3-piperidin-1-yl-propyl)-5-trifluoromethyl-phenyl]-acetamide.

Quellen und Nachweise

ORD-Eintrag
ord-6cba07ca4b0b40b99888a42cfdde22bf
Quelldatensatz
uspto-grants-2012_08
Patentnummer
US08247556B2

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