HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Bromo-2,3-dihydro-1-benzofuran → (3R)-1-(2,3-dihydro-1-benzofuran-5-yl)-3-methylpiperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Bromo-2,3-dihydro-1-benzofuran | HCID 2776159 | — |
| Edukt | (3R)-1-(3,4-dimethoxyphenyl)-3-methylpiperazine | HCID 58487959 | — |
| Produkt | (3R)-1-(2,3-dihydro-1-benzofuran-5-yl)-3-methylpiperazine | HCID 11651447 | — |
Reaktionsschritte
The title compound was prepared following the procedure of Intermediate 25, but starting from 5-bromo-2,3-dihydrobenzo[b]furan. Purification by flash chromatography (CHCl3/MeOH) gave the title compound as a brown oil. M+(ESI): 219.2. HPLC (Condition A), Rt: 1.3 min (HPLC purity: 99.9%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08247437B2 |
| Quelldatensatz | uspto-grants-2012_08 |
| ORD ID | ord-c5f72056f07d470da389ea08d9d675b5 |
| Quellennotiz | uspto-grants-2012_08 |