2,2,2-Trifluoroethyl Methanesulfonate → 2-Methyl-4-[2-methyl-1-(2,2,2-trifluoro-ethyl)-1H-imidazol-4-ylethynyl]-pyridine
Reaktionsgleichung
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.S(O[CH2:21][C:22]([F:25])([F:24])[F:23])(=O)(=O)C>>[CH3:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([CH2:21][C:22]([F:25])([F:24])[F:23])[CH:14]=2)[CH:5]=[CH:4][N:3]=1Komponenten
3
Versuchsvorschrift
The title compound, MS: m/e=280.1 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2,2,2-trifluoroethyl mesylate.
Quellen und Nachweise
- ORD-Eintrag
- ord-08a2d881db674a16b9f53b7e318f89a5
- Quelldatensatz
- uspto-grants-2006_08
- Patentnummer
- US07091222B2
Notizen zur Reaktion
Wird geladen…