HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide → 4-Methyl-1-(4-(trifluoromethyl)phenyl)pentan-1-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide | HCID 14069348 | — |
| Edukt | HCID 178418529 | HCID 178418529 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 4-Methyl-1-(4-(trifluoromethyl)phenyl)pentan-1-one | HCID 46941396 | 77% |
Reaktionsschritte
With the similar conditions of Example 29, steps (a) and (c), reaction of N-Methoxy-N-methyl-4-trifluoromethyl-benzamide, compound 31 a, with 3-methyl-1-butyl magnesium bromide, compound 29a, in THF gave the title compound in 77% yield; Calcd MW 244.26. Found MH+ 245.2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08247610B2 |
| Quelldatensatz | uspto-grants-2012_08 |
| ORD ID | ord-42b29be0db1342bfaf79a46419c91ce7 |
| Quellennotiz | uspto-grants-2012_08 |