1-(Bromomethyl)-2-(methylsulfanyl)benzene → 4,4-Dimethyl-1-[2-(methylthio)benzyl]-2-(adamantan-2-yl)-1,2-diazetidin-3-one
Reaktionsgleichung
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[N:11]1[C:14](=[O:15])[C:13]([CH3:17])([CH3:16])[NH:12]1)[CH2:8]2.[CH3:18][S:19][C:20]1[CH:27]=[CH:26][CH:25]=[CH:24][C:21]=1[CH2:22]Br>>[CH3:16][C:13]1([CH3:17])[N:12]([CH2:22][C:21]2[CH:24]=[CH:25][CH:26]=[CH:27][C:20]=2[S:19][CH3:18])[N:11]([CH:2]2[CH:3]3[CH2:4][CH:5]4[CH2:6][CH:7]([CH2:8][CH:1]2[CH2:10]4)[CH2:9]3)[C:14]1=[O:15]Komponenten
3
Versuchsvorschrift
2-(Adamantan-2-yl)-4,4-dimethyl-1,2-diazetidin-3-one and 2-(methylthio)benzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a white crystalline powder.
Quellen und Nachweise
- ORD-Eintrag
- ord-3e1afde289b54d7eb99e07f294ebd441
- Quelldatensatz
- uspto-grants-2012_08