1-(Bromomethyl)-2-chloro-4-fluorobenzene → 1-(2-Chloro-4-fluorobenzyl)-2-cyclohexyl-4,4-dimethyl-1,2-diazetidin-3-one
Reaktionsgleichung
[CH:1]1([N:7]2[C:10](=[O:11])[C:9]([CH3:13])([CH3:12])[NH:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:14][C:15]1[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:16]=1[CH2:17]Br>>[Cl:14][C:15]1[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:16]=1[CH2:17][N:8]1[C:9]([CH3:13])([CH3:12])[C:10](=[O:11])[N:7]1[CH:1]1[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Komponenten
3
Versuchsvorschrift
2-Cyclohexyl-4,4-dimethyl-1,2-diazetidin-3-one and 2-chloro-4-fluorobenzyl bromide were used for a similar reaction and treatment as Process 6 of Example 1, and the title compound was obtained as a colorless oil.
Quellen und Nachweise
- ORD-Eintrag
- ord-4536c05d31b24439adbb63c2d5c5a68b
- Quelldatensatz
- uspto-grants-2012_08