Ethyl chloroformate → HCID 68675322, Verbindung

HRID 889161Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 889161
Cl[C:2]([O:4][CH2:5][CH3:6])=[O:3].[IH:7].[CH3:8][N:9]1[CH2:13][CH2:12][N:11]=[C:10]1[NH:14][NH2:15]>N1C=CC=CC=1>[IH:7].[CH2:5]([O:4][C:2]([NH:15][NH:14][C:10]1[N:9]([CH3:8])[CH2:13][CH2:12][N:11]=1)=[O:3])[CH3:6]

Komponenten

4

Edukt 2

HCID 10928Ethyl chloroformateHCID 2145886149541-82-4

Produkt 1

HCID 68675322HCID 68675322, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

Ethyl chloroformate (0.95 ml) was added dropwise to a mixture of (1-methyl-4,5-dihydro-1H-imidazol-2-yl)-hydrazine hydroiodide (CAS 49541-82-4) (2 g) and pyridine (40 ml) while stirring, and the mixture was stirred at room temperature for 2 hours. The solvent was distilled off and the residue was purified by silica gel column chromatography. The obtained compound was washed with diethyl ether to obtain the title compound (1.14 g).

Aufarbeitung

  1. stirringthe mixture was stirred at room temperature for 2 hours
  2. distillationThe solvent was distilled off
  3. customthe residue was purified by silica gel column chromatography
  4. washThe obtained compound was washed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-2e0b6e814d9f4028b7332515d872a272
Quelldatensatz
uspto-grants-2012_08
Patentnummer
US08252810B2

Notizen zur Reaktion

Wird geladen…