Acrylonitrile → HCID 22250584, Verbindung

HRID 890247Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 890247
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([CH3:11])=[CH:7]2.[C:12](#[N:15])[CH:13]=[CH2:14]>O1CCOCC1>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:14][CH2:13][C:12]#[N:15])[C:8]([CH3:11])=[CH:7]2

Komponenten

4

Edukt 2

HCID 7855AcrylonitrileHCID 118160627-chloro-2-methyl-1H-indole

Produkt 1

HCID 22250584HCID 22250584, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel2×

Reaktionsbedingungen

Temperatur
60 °C

Versuchsvorschrift

20 g of 7-chloro-2-methyl-1H-indole are mixed in 100 ml of dioxane with 3 g of triton B, 3 g of acrylonitrile are slowly added, 250 ml of dioxane are added again and then the mixture is heated at 60° C. for 2 hours. The medium is evaporated and then the residue is taken up in AcOEt. The precipitate formed being removed, the product obtained is used as is in the following stage.

Aufarbeitung

  1. additionare slowly added
  2. customThe medium is evaporated
  3. customThe precipitate formed
  4. custombeing removed
  5. customthe product obtained

Quellen und Nachweise

ORD-Eintrag
ord-ba29b17d0fe24ef58b35fa9cc419cc88
Quelldatensatz
uspto-grants-2006_02
Patentnummer
US06995184B2

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