HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5,12-Naphthacenedione → Doxorubicin
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5,12-Naphthacenedione | HCID 14160 | — |
| Edukt | Doxorubicin Hydrochloride | HCID 443939 | — |
| Produkt | Doxorubicin | HCID 31703 | — |
Reaktionsschritte
Doxorubicin hydrochloride, 5,12-Naphthacenedione, (8s-cis)-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-hydrochloride (hydroxydaunorubicin hydrochloride, Adriamycin) is used in a wide antineoplastic spectrum. It binds to DNA and inhibits nucleic acid synthesis, inhibits mitosis and promotes chromosomal aberrations.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07005424B2 |
| Quelldatensatz | uspto-grants-2006_02 |
| ORD ID | ord-d8beeddac0a94a5590148f0b1fc8a0b9 |
| Quellennotiz | uspto-grants-2006_02 |