HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 892355Erstellt: 25. Oktober 2026
Potassium Hydroxide → 7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one
https://huagongshe.com/reaction/892355
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | 2-chloro-N-(2-hydroxy-4-nitrophenyl)acetamide | HCID 19968389 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | 7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one | HCID 2763830 | 85% |
Reaktionsschritte
A mixture of 8 (22 g) and powdered KOH (6.9 g) in DMSO (100 ml) was stirred at 95° C. for 30 min. and poured onto crushed ice (400 g). The resulting precipitate was collected and washed with H2O to give 9 (15.7 g, 85%): mp 230°-232° C.; MS m/e 194 (M+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US05118323 |
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| Quelldatensatz | uspto-grants-1992_06 |
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| ORD ID | ord-0b33cd03661144cdbccc1cf78e75bb00 |
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| Quellennotiz | uspto-grants-1992_06 |
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